Chronic Obstructive Pulmonary Disease
January 1st, 2012Both hypoxemia and hypercapnia can develop during sleep in patients with chronic obstructive pulmonary disease. Respiratory impairment is more severe during REM sleep compared with NREM sleep. Hypoxemia, the extent of which is related to the percentage of REM sleep in relation to total sleep time and daytime levels of PaCO2, PaO2, and oxygen saturation [...]